itt egy thread erről: [link]

Should we wait for an Omicron-specific booster? Short answer: No
[...]
2 weeks later, the team checked the neuts levels from each arm against various viral strains.
For ALL strains the neuts level of Arm2⃣ (Omi💉) were NOT better than Arm1⃣ (WT💉)
This was also true for Omicron 😳. Look at gray lines at w#43 in both graphs (WT: solid; O: broken)

Why? This is probably the Original Antigen Sin (OAS). The immune system already learned how a WT Spike protein looks like and lost some plasticity to learn the nuances of Omicron-spike. For non-scientists: think about it as if you're trying to speak in a foreign language

After a certain age, no matter how hard you try, you still have a specific accent of your mother tongue and you cannot forget it. The same is true for your immune system: it cannot unlearn the "accent" of a WT spike.

s it totally bad? I don't think so! First, it means that we don't need to wait for anything and @pfizer /@moderna_tx can produce at full speed the current vaccine. Moreover, 🇮🇱MoH recently showed that a fresh 4th dose really helps against O-infection and severe cases.